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Flupirtine maleate

CAS No. 75507-68-5

Flupirtine maleate ( D-9998 )

Catalog No. M15872 CAS No. 75507-68-5

A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 41 Get Quote
50MG 50 Get Quote
100MG 69 Get Quote
200MG 111 Get Quote
500MG 266 Get Quote
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Biological Information

  • Product Name
    Flupirtine maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
  • Description
    A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties; a centrally acting non-opioid analgesic used as an analgesic for acute and chronic pain.Pain Discontinued
  • Synonyms
    D-9998
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    NMDAreceptor;PotassiumChannel
  • Research Area
    Neurological Disease
  • Indication
    Pain

Chemical Information

  • CAS Number
    75507-68-5
  • Formula Weight
    420.39
  • Molecular Formula
    C19H21FN4O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 40 mg/mL
  • SMILES
    CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=C\C(=O)O)\C(=O)O
  • Chemical Name
    Carbamic acid, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester, (2Z)-2-butenedioate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Szelenyi I, et al. Inflamm Res. 2013 Mar;62(3):251-8.
2. Harish S, et al. J Anaesthesiol Clin Pharmacol. 2012 Apr;28(2):172-7.
3. Hedegaard ER, et al. J Pharmacol Exp Ther. 2016 Apr;357(1):94-102.
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